compound dysplastic melanocytic nevus

compound dysplastic melanocytic nevus

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DOI: cnki: ISSN :1671-3141 .0.2
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Background: The s found a special abnormal proliferation of melanocytes within the epidermis phenotype, does not meet the dysplasia classification of melanocytic nevi, but its morphology is still not diagnosed as melanoma in situ. The s named this new skin lesions within the epithelioid melanocytic dysplasia. Methods: 75 patients from the 82 skin biopsies have shown that the morphology of this particular performance. The Soviet UnionCAJ format PDF format and supportSpecial Note: This document summary information, provided by China Knowledge Network, wooden worm only indexes the full text does not provide free s.
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Documents were cited China Academic Journal ago 10 1 Wu Lili, Zhan Rong Chau; the nasal cavity in 8 cases of primary malignant melanoma pathological analysis [J]; Diagnostic Pathology; 1997 02 2 Zhang Xin, Zhou Jianhua, Xiao Jianyun, Snow Cheng, JIANG Hai-ying; nasal malignant melanoma immunohistochemical study with clinical observations [J]; World Journal of Surgery; 1999 01 3 Wenbin, ZHOU Ji-Yong, Huang Yi-fan; nasal cavity in 15 cases of primary malignant melanoma report [J]; North Sichuan Medical College; 1997 03 4 Xuya Hui, Feng Qingjie; total nasal septum resection in malignant melanoma [J]; Department of Otolaryngology - Head and Neck Surgery; 1997 03 5 Zhou Jianhua, JIANG Hai-ying, Fu Chun-yan, LIU Yan, Xi Jianmin; nasal amelanotic malignant melanoma immunohistochemical study [J]; Hunan Medical; 1999 06 6 Chi Min, Wang Shu Yi; Otolaryngology malignant melanoma 40 cases [J]; Clinical Journal of Otorhinolaryngology; 7 Humeng Jun 05, 2004! 311800; nasal cavity in 5 cases of primary malignant melanoma study [J]; Antimicrobial Agents and Chemotherapy; 2001 08 8 Xu Chao, Wang Ying, Sun Xing Hong, Su Zhifeng; 20 cases of malignant melanoma of the clinical and pathological analysis [J]; Practical Oncology; 2003 02 9 Zhao Yulin, Dongming Min, Lou Weihua, Lui Ming Shuan; nasal cavity malignant melanoma of 9 Cases [J]; new medicine; 12, 2002 of Chapter 10 Mei Zhen, Li-Chuan Wu; District Primary anorectal malignant melanoma (with report of three cases) [J]; of Clinical Oncology and Rehabilitation; 1997 01
Malignant melanoma is a very high degree of malignancy, also known as malignant melanoma, most of the primary in the skin, also originated in the eyes, nose, etc., early transfer may occur, more common metastatic sites of lung and brain. Once the diagnosis of extensive tumor resection as soon as possible, and comprehensive measures to assist the immune treatment. Melanoma (melanmoa), also known as malignant melanoma, is a highly malignant melanoma can produce, mostly found in adults over 30 years old, occurred in the skin are sufficient to meet the bottom and more common around the vulva and anus, you can start is the malignant, but usually comes from the junction of malignant moles. Where the pigment mole deepened, the volume increases, the growth speed up or ulceration, inflammation and bleeding is often a symbol of malignant transformation. The tumor may also occur in the mucous membranes and internal organs. Melanoma showed a diversity of organizational structure, tumor cells showed nests, cords or acinar-like arrangement. Tumor cells were polygonal or spindle, and a large, often thick eosinophilic nucleoli, melanin granules within the cytoplasm. There is no melanin granules within the cytoplasm of melanoma, called non-melanoma, but the DOPA reaction was positive. Electron microscope, can be reflected in its cytoplasm contains a few typical melanosome (melanosome) or former melanosome (premelanosome), assist in diagnosis. Most of the poor prognosis of melanoma, late may have lymph node metastasis and blood. Therefore, this tumor of early diagnosis and prompt treatment is very important.
Malignant melanoma is a very rare malignant cancer, moles, also known as cancer or nevi, often family history, mostly autosomal dominant inheritance. Banana spots like malignant mole, dysplastic melanocytic nevi, junctional nevi moles or other dark piles of unknown etiology, generally considered the endocrine related, by the prolonged exposure to sunlight, trauma stimuli, incomplete burning or a biopsy, immunocompromised virus infection can induce the disease.
Subungual malignant melanoma mostly occurs in middle-aged and elderly men and slightly more than females, occur in the lower extremities, common in the toe. This case is not obvious because early symptoms, no increase was misdiagnosed mind, combined with the first attending physician lack of knowledge of the disease, only in the paronychia, subungual treatment of other diseases, to pull A, debridement, resulting in stimulation of malignant tumors , caused by exacerbations, tumor rupture, after bleeding, suppuration, ipsilateral inguinal lymph node was able to diagnosis, should be considered as lessons learned.
From the misdiagnosis of cases seen in a long time, where the following cases, both doctors and patients should expect the possibility of malignant melanoma: there is a dark brown or black line under the lesion suddenly increased, particularly in the more than 45 years of age; (toe) the persistence of a post-traumatic symptoms following damage; disease progression is rapid, severe local ulceration; by a person under the prolonged unhealed injury treatment. A cut should be timely, organized for pathological examination and early diagnosis.
Under a diagnosis of malignant melanoma, once established, should be promptly cut the line (toe) surgery. Longer course, or those of regional lymph nodes, regional lymph node dissection should be timely, necessary, immune and interferon combination therapy may increase efficacy. Avoid incomplete resection or chemical burn, but to promote their proliferation or transfer, should be seen as taboo.
Benign melanoma completely removed, the prognosis is good. But once they are assessed as malignant that even surgery can not cure, because there are 30 to 70% of the cases will be transferred. There are reports that after resection of small malignant melanoma, it can survive 12 months, but within 2 years the mortality rate of 54%. If the removal of a wide range of malignant melanoma, can survive for 4 months, but within 2 years the mortality rate was 100%. In addition to surgical resection, in addition to the use of radiation, local temperature, chemical treatments. Radiation therapy has been successfully used in the control melanoma, after surgical removal may be the most effective treatment.Melanoma symptoms vary by type, in the case of nodular who uplift since the beginning of the dark blue nodules, and around to flush, increases rapidly, rupture, early metastasis; if superficial diffusion, initial from the macula, the latter into a nodule, 2.5 cm diameter, often has curved, brown, black, pink or even gray or white. In addition, there are malignant freckle type commonly used in clinical remedies, prescription mainly as follows.
[Side A]
Denmark: mercury, alum, green vitriol, saltpetre each 180 grams, 90 grams of salt.
Paste: 18 grams on the crystallization of Denmark, Toad, Matchmaker, cantharidin, 0.5 grams, 1 gram of powder Yangjinhua.
side of the drug mixture a total of research, to not see the water beads for the degree, the heat transfer''re welcome, steam to water, so as "Dan tire" and then in the bowl upside down You''re welcome, the salt placed in plaster after sealing lotus leaf altar, the altar built of about 10 kg of water, put the tank about 2 hours after the charcoal heating, cooling bowl, remove the powder (a white crystalline is better), and research fine after the Fab Five, Dan. side of the drug into a paste that is prepared to batter too. When the coating on the surface with cancer.
From the side "of Traditional Chinese Medicine," 1982.4, functional convergence sore myogenic remove rot, suitable for malignant melanoma.
[Side b]
Kiwi 250 grams, 500 grams of dog meat, eggs or pork 2 amount, kiwi root 120 grams. First with the kiwi and dog meat stew were served, after a day with Kiwi roots, eggs and pork stew served amount, 30 grams for a course of treatment.
The side from the "Fujian medical and health," 1976.2, malignant melanoma of the eye and effective.
[Third Party]
Chrysanthemum, seaweed, triangular, Zedoary, Codonopsis, Astragalus, Yinhua, tonkinensis, mountain arrowhead, Loulu, berberine, each 100 grams, fleas off, Iris son of the 75 grams, the system Strychnos, the system centipede 50 grams of Lithospermum 25 grams, 15 grams of cooked rhubarb. Joint research to fine the drug, with amethyst 100 grams, 2000 grams of calcined red yellow vinegar placed in the water, cooling after the filter, this vinegar for the pill, such as the Indus child large, daily 2 - 3 times, each time 25-30 tablets, 1 hour after meals with warm water
Service, fast spicy food.
From the side "of Traditional Chinese Medicine," 1982.4, function Qingrejiedu swelling, adapted to malignant melanoma.
[Side Four]
Bezoar 50 grams, 30 grams of musk, borneol 40 grams, berberine 90 grams, 120 grams of borax, realgar 60 grams, 100 grams of green beans, Shishuang amount. Total to fine, refined honey for the pills, weight 1.5 grams per pill. Every time a pill, daily 3 - 4 times, hold in mouth of. 20 to 1 course of treatment, once a 2 - 3 after treatment withdrawal, 1 month after taking.
The side from the "cancer treatment in Western medicine Filmography", function Qingrejiedu, Xiaoban Sanjie for flaming due to toxic heat caused the throat of malignant melanoma.
[Side V]
Rehmannia 15-30 grams, 15-30 grams of Qi fruit, cornus 15 grams, fleece-flower root, Polygonatum each 30 grams, 15 grams of Poria, black sesame, black beans, 30 grams, 15 grams paeonol, Ampelopsis, horsetails, 30 each grams. 1 day, Shuijianbi.
The side from the "cancer treatment in Western medicine Filmography", nourishing the liver and kidney function, for malignant melanoma is a liver and kidney deficiency type.
[Side Six]
Gall powder, cork powder, indigo, dried alum end of the rubber end of the Shengjisan 2 copies, pearl powder 1. Mixing the powder and set aside, each with a little, local application.
The side from the "herbal cancer prevention and control Handbook", function cured myogenic rot, fester for malignant melanoma is difficult convergence.
[Party VII)
Gentian 6 grams, 9 grams of Scutellaria, Gardenia 6 grams, 10 grams Alismataceae, Akebia, Plantago 6 grams each, parsley, 10 grams of raw land, Bupleurum 5 grams, 10 grams of castor seed moss, capillaris 15 grams, 10 grams of talc, 6 grams of licorice. 1 day, Shuijianbi.
The side from the "cancer treatment in Western medicine Filmography", functional spleen dampness, for malignant melanoma Spleen wet Sheng type.
[Side Eight]
Angelica, Astragalus, 15 grams, 9 grams of skullcap, 15 grams of raw land, cultivated land 9 grams, aspartame, Ophiopogon of 10 grams, 9 grams of trichosanthin, safflower, peach kernel of 6 grams, Chuanxiong 10 grams, 15 grams of white peony root, fleece-flower root 20 grams, 6 grams of licorice. 1 day, Shuijianbi.
The side from the "Great Integrative Medicine Cancer Clinic", function nourishing and moisturizing for melanoma patients is a deficiency of air dry.
[Side Nine]
50 grams of astragalus, ginseng 4 grams (according to the disease are often used in red ginseng, American ginseng, Sun-dried ginseng, so in the Senate, Codonopsis), fried Bai Zhu, Fu qin, 15 grams, 10 grams of Angelica, white peony root 30 grams, 20 grams of raw land , Dendrobium 10 grams, Actinidiae, Maozhaocao, 30 grams each of Hedyotis diffusa, Prunella 10 grams, 20 grams of Paris polyphylla, stone see the clothing, turtle shell, 10 grams, 30 grams of Coix. 1 day, Shuijianbi.
The side from the "Chinese ADULT" 19 soles. 15, function Ziyin heat, nourishing blood, blood detoxification, for malignant melanoma.
[Fang ten]
Gall powder, cork powder, indigo, dried alum end of the rubber end of the Shengjisan 2 copies, pearl powder 1. Mixing the powder and set aside, each with a little, local application.
The side from the "herbal cancer prevention and control Handbook", function cured myogenic rot, fester for refractory malignant melanoma.
[Side XI]
Rehmannia 10 grams, 15 grams of turtle shell, cork 10 grams, Anemarrhena 12 grams, 10 grams of yam, cornus 9 grams, Dan, 10 grams medlar, Dendrobium 15 grams, 6 grams Zhigancao. 1 day, Shuijianbi.
The side from the "Great Integrative Medicine Cancer Clinic." Yin Jiang Huo features for melanoma is a yin deficiency heat card.
[Side-second]
Black fungus 39 grams, 30 grams of wood thieves, Scrophulariaceae 12 grams, 30 grams of oysters, Prunella 60 grams, 12 grams orange, heavy floor, Jing skin, Scutellaria barbata 30 grams each, Duchesnea indica, the Indian Hedyotis diffusa grams. Decoction 2, morning and evening hours service, day
The side from the "Sichuan Traditional Chinese Medicine," 1983.5, functional detoxification, blood circulation reduces swelling, for malignant melanoma.
[Side Thirteen]
Radix, Woodwardia, Jing leather, wood thieves, weight 30 grams each floor, Scrophulariaceae 15 grams, 20 grams of oysters, Duchesnea indica, Scutellaria barbata, Hedyotis diffusa each 60 grams, 30 grams of black fungus. Decoction 2, morning and evening hours service, day
The side from the "Sichuan Traditional Chinese Medicine," 1983.5, function Qingrejiedu swelling, adapted to malignant melanoma.know reproduced